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Architecture of the Photosynthetic
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1S5L.pdb - Welcome from the authors
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| Kristina N. Ferreira*, Tina M.
Iverson*, Karim Maghlaoui, James Barber†, and So
Iwata†
* these authors contributed equally to the work; † to whom correspondence should be addressed Full publication: Science. 2004 Mar 19;303(5665):1831-8. Epub 2004 Feb 05 |
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| ABSTRACT Photosynthesis uses light energy to drive the oxidation of water at an oxygen-evolving catalytic site within photosystem II (PSII). We report the structure of PSII of the cyanobacterium Thermosynechococcus elongatus at 3.5 Å resolution. We have assigned most of the amino acid residues of this 650 kDa dimeric multisubunit complex and refined the structure to reveal its molecular architecture. Consequently we are able to describe details of the binding sites for cofactors and propose a structure of the oxygen-evolving center (OEC). The data strongly suggest that the OEC contains a cubane-like Mn3CaO4 cluster linked to a fourth Mn by a mono-µ-oxo bridge. The details of the surrounding coordination sphere of the metal cluster and the implications for a possible oxygen-evolving mechanism are discussed. | ||
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Site design: Dr. Jon
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© ScienceExpress, © Wolfson
Laboratories, Department of Biological Sciences, Imperial College London,
2004